Jane, I think we actually discussed this when you were up here, but if you want some advice (which you probably don't)--we dealt with cancer with our collie Ethel for over a year. It simply wasn't worth it in the long run (we spent probably close to $3000 in treatment). Ultimately the cancer got her and her quality of life for the last year was not what she was used to, especially after her second or third surgery. I think Betsy would tell you the same thing--keep Echo as pain free as possible, but if it isn't possible, do the humane thing and send her to her maker. It's a horrible choice, I know--we've had to do it twice with our elderly female dogs in the last couple of years.