TOD
THe optifast has been the most successful although it is hard to keep to it stictly. I have lost almost 50lbs
My friend Margo went through Optifast twice. She gained back the weight both times. About 15 years ago, she wanted to adopt another baby from China and not have to buy two airplane seats for herself, so she looked at other options. Gastric bypass was not something that she was going to consider, at all. We went to a presentation of a program offered through (but not by) Group Health called Health Management Resources (HMR). It was like Optifast (all or mostly meal replacement shakes), but not as calorically restrictive, and medical testing wasn't necessary.
On a whim, I decided to do it also, so we both went through the program. I lost 122 pounds, but the company didn't want to send two people from Seattle to Olympia once a week anymore and the program ended for us. Reality set in and we both gained back most of the weight...not all, but most. Coincidentally, we recently decided to do the HMR shakes again on our own, although not full bore. I've actually started changing some of the things that I eat, and have lost some weight already.