I know nothing about OMEPROZOLE, but heartburn is just one type of "tummy trouble." There are many things that can be wrong, completely apart from heartburn. Most people benefit from taking digestive enzymes with meals, as digestive capacity is one of the things that declines as we age. Heartburn, on the other hand, is usually from eating too many acid foods--meat, dairy, sugar--and not enough alkaline foods--veggies. My favorite way to deal with heartburn is to drink a glass of alkaline (bottled ) water. Most stores carry alkaline water these days. It must be alkaline water, though--not just any bottled water. Believe me, it stops the heartburn immediately with just a few ounces. It's inexpensive and easy to keep on hand. You can also drink it daily to avoid heartburn in the first place.