It's the drugs.
Don't be worried. She was sedated, and that knocks some of them for a loop. Our boy Poe isn't himself the rest of the day when he's had that. And we saw it a few years back in little Kali, who was built more like Annabelle. In fact, one of the times she was sedated she was weird for TWO days.
All you really have to do is watch over them as it slowly wears off. Try not to let her climb up high, for instance, lest she lose her balance. And don't worry if her appetite's off.