I've read that Bette Davis was devastated when Mike Nichols didn't offer her Martha in the film version of WHO"S AFRAID OF VIRGINIA WOOLF. But honestly, as much as I love much of her work, I can't picture her in the part. Oh, the act I braying would be right up her alley, but by act III, I can't see her pulling off Martha's collapse.
Maybe I've just seen Liz and the film too many times to consider it anything but perfect the way it is.