Very true that neither Grace, Jack, nor Karen resemble anything remotely human on WILL & GRACE any more. (They can still make me laugh with their outrageous shenanigans, however). Of the principals, only Eric McCormack has attempted to keep Will on anything like a human plane of existence, and I find his acting choices very interesting on the show.
I was delighted that the writers brought Vince (Babby Canavalle) back into WIll's life last night, and it's my expressed hope a happy reconciliation can be worked out between them. Nothing would make me happier than to have the first long-running network gay main character to end up happily in TV syndication heaven.