I really don't think I need to sanitize the whole house, Ricky has only been in the bedroom. I've been using the cream for a week and it doesn't seem to be getting better, it's a little worse today. I've read a lot about the baths and decided to try it. The vet wants him to take meds, I don't really want to do that, but we'll see how it goes. I am going to clean one room a night. I'm not going to necessarily use bleach on every surface, but I will deep clean. I figure it can't hurt.